Peer-reviewed veterinary case report
Cat nasal granuloma caused by Cryptococcus gattii
By Cardoso, Pedro Henrique Magalhães et al.·Published in Mycopathologia·2013·Departamento de Microbiologia, Brazil·View original on PubMed →
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Original publication title: Feline nasal granuloma due to Cryptoccocus gattii type VGII.
- Species:
- cat
Plain-English summary
A cat with a nasal granuloma (a type of growth) was diagnosed with an infection caused by a fungus called Cryptococcus gattii. After testing, the vet determined that the cat was susceptible to several antifungal medications. The cat was treated with a combination of itraconazole and 5-flucytosine, which successfully cleared the granuloma after six months of treatment. This case highlights the importance of identifying the specific fungus to ensure effective treatment.
People also search for: cat nasal growth treatment · Cryptococcus gattii in cats · antifungal medication for cats
Abstract
The aims of this study are to make a more precise identification of the etiologic agent of a nasal granuloma in a cat, to verify the susceptibility to the antifungal drugs: ketoconazole, itraconazole, fluconazole, posaconazole, voriconazole, amphotericin B and the proper treatment. Part of the granuloma's fragment was removed, added to a saline solution and sent to the Laboratory of Mycology. The solution was then seeded in Sabouraud dextrose agar, and the yeast was primarily identified by the traditional methods. The confirmation of the specie Cryptococcus gattii and its molecular type were performed using the PCR-RFLP molecular techniques. The antifungal susceptibility was verified by using the E-test method, and the cat was treated with itraconazole associated with 5-flucytosine. The isolated strain was identified as C. gattii type VGII and was susceptible to all antifungal drugs tested. The treatment with itraconazole associated with 5-flucytosine led to the cure of granulomatous lesions in the feline after 6 months. The characterization and molecular investigation of this microorganism are relevant because they could help us better understand the epidemiology of the infection and to guide us to treat properly the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23943404/