Peer-reviewed veterinary case report
Antibody responses in kittens after two types of FVRCP vaccines
By Lappin, Michael R·Published in Journal of feline medicine and surgery·2012·Department of Clinical Sciences Colorado State University, United States·View original on PubMed →
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Original publication title: Feline panleukopenia virus, feline herpesvirus-1 and feline calicivirus antibody responses in seronegative specific pathogen-free kittens after parenteral administration of an inactivated FVRCP vaccine or a modified live FVRCP vaccine.
- Species:
- cat
Plain-English summary
A group of kittens received either an inactivated or a modified live vaccine to protect against feline panleukopenia, feline calicivirus, and feline herpesvirus. The kittens were monitored for their immune response over 49 days. Those given the modified live vaccine showed a quicker immune response to panleukopenia, while the inactivated vaccine led to a faster response to herpesvirus. By day 14, all kittens had developed immunity to the viruses. Both vaccines were effective, but they worked at different rates for different viruses.
People also search for: kitten vaccine response · feline panleukopenia vaccine effectiveness · cat herpesvirus vaccine comparison
Abstract
Two groups of feline panleukopenia (FPV), feline calicivirus (FCV) and feline herpesvirus 1 (FHV-1) seronegative kittens (six cats per group) were administered one of two feline viral rhinotracheitis, calcivirus and panleukopenia (FVRCP) vaccines subcutaneously (one inactivated and one modified live) and the serological responses to each agent were followed over 49 days (days 0, 2, 5, 7, 10, 14, 21, 28, 35, 42, 49). While the kittens administered the modified live FPV vaccine were more likely to seroconvert on day 7 after the first inoculation than kittens administered the inactivated vaccine, all kittens had seroconverted by day 14. In contrast, FHV-1 serological responses were more rapid following administration of the inactivated FVRCP vaccine when compared with the modified live FVRCP vaccine. There were no statistical differences between the serological response rates between the two FVRCP vaccines in regard to FCV.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22314095/