Peer-reviewed veterinary case report
Feline pemphigus foliaceus skin disease signs and treatment outcomes
By P. Bizikova & A. Burrows·Published in BMC Veterinary Research·2019·View original on Semantic Scholar →
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Original publication title: Feline pemphigus foliaceus: original case series and a comprehensive literature review
- Species:
- cat
Plain-English summary
A group of cats diagnosed with pemphigus foliaceus, a skin condition that causes crusty sores mainly on the face and feet, showed symptoms like lethargy, fever, and loss of appetite. Most of these cats responded well to treatment with glucocorticoids, a type of steroid medication, and many achieved control of their symptoms quickly. However, since this condition can come back, long-term treatment is often necessary. Owners should be aware of the possibility of relapses to help manage their cat's health effectively.
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Abstract
BackgroundSince the first description of feline pemphigus foliaceus (PF) more than 30 years ago, numerous case reports have been published, while larger case series have remained rare. This large body of information, if extrapolated, could address clinical discrepancies and expand our knowledge about the treatment of feline PF.This manuscript reviews cases of feline PF published between 1950 and 2016 and adds additional 35 original cases to provide further insight into the clinical aspect and treatment outcome of this disease.ResultsFeline PF, while being a primary acantholytic pustular dermatosis, presents most often with crusts and erosions that predominantly affect the face and feet. More than half of cats with active disease exhibits non-dermatological signs such as lethargy, fever and/or anorexia. The prognosis of feline PF is good as the majority of cats rapidly achieve disease control even with the most basic treatment such as glucocorticoid monotherapy. Most PF-affected cats, however, require long-term treatment and, like other autoimmune diseases, feline PF has a tendency to relapse spontaneously or with treatment changes.ConclusionsTherefore, despite the overall good prognosis cats with PF can be given, owners should be informed and prepared for these circumstances, which may reduce the risk of euthanasia in the case of disease relapse, and improve treatment compliance.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/30626385