Peer-reviewed veterinary case report
Swollen and ulcerated cat footpads caused by plasma cell
By Dias Pereira, Patrícia & Faustino, Augusto M R·Published in Veterinary dermatology·2003·ICBAS - Instituto de Ciê·View original on PubMed →
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Original publication title: Feline plasma cell pododermatitis: a study of 8 cases.
- Species:
- cat
Plain-English summary
A group of cats with swollen and ulcerated footpads were diagnosed with a condition called plasma cell pododermatitis. This condition can affect any cat, regardless of sex, breed, or age. In the cases studied, treatment with glucocorticoids (a type of steroid) helped four cats completely recover, while two others had surgery to remove the affected tissue, which also led to full recovery. Overall, the cats showed significant improvement and their symptoms resolved over time.
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Abstract
Eight cases of feline plasma cell pododermatitis, collected over a 3-year period, were studied using histological (haematoxylin and eosin), histochemical (methyl green-pyronin) and immunohistochemical (antibody against lambda light chains of immunoglobulins) techniques. No sex, breed or age predisposition, or paw predilection was observed. The disease began as a swelling of the footpads, followed by ulceration. Histologically, lesions were characterized by the presence of a large number of plasma cells in a predominantly perivascular pattern. Binucleated plasma cells and mitotic figures were observed. Clinical follow-up for over 1 year revealed total remission of the lesions both after glucocorticoid therapy in four cases, and total surgical excision in two animals. Follow-up studies were not possible in one case.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14678445/