Peer-reviewed veterinary case report
Feline skin lesions in sporotrichosis linked to fungal load
By Miranda, Luisa H M et al.·Published in Comparative immunology, microbiology and infectious diseases·2013·Laborató, Brazil·View original on PubMed →
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Original publication title: Feline sporotrichosis: histopathological profile of cutaneous lesions and their correlation with clinical presentation.
- Species:
- cat
Plain-English summary
A group of cats with sporotrichosis, a fungal skin infection, were studied to understand how the severity of their skin lesions related to their overall health. The researchers found that cats with lesions in multiple areas had a higher fungal load and more severe symptoms, while those with localized lesions tended to have a better general condition and lower fungal levels. Skin biopsies showed that the type of granulomas (a type of inflammatory response) varied, with poorly formed granulomas linked to more severe cases. Managing the fungal load in cats with localized lesions could lead to better recovery outcomes.
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Abstract
Cutaneous lesions of feline sporotrichosis show high fungal load and are associated with severe disease and elevated zoonotic potential. The present study describes the histopathology and fungal load of the lesions in different clinical presentations of feline sporotrichosis. Cats with sporotrichosis were separated into groups L1, L2 and L3 (lesions in one, two and three or more locations, respectively) and subjected to skin biopsies for histopathology. Eighty-six cats were included in the study. Lesions were suppurative granulomatous in 84 cases and poorly formed granulomas were predominant. The well-formed granulomas were associated with group L1. The high fungal load was predominant in group L3 and in poorly formed granuloma cases and did not occur in well-formed granulomas cases. The good general condition was associated with low fungal load. These findings suggest that the fungal load control in animals with more localized lesions and well-organized response is linked with the improvement in the outcome of infected cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23623733/