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Peer-reviewed veterinary case report

Thyroid cancer in cats and high-dose radioactive iodine treatment

By Hibbert, Angie et al.·Published in Journal of feline medicine and surgery·2009·Department of Clinical Veterinary Science, United Kingdom·View original on PubMed

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Original publication title: Feline thyroid carcinoma: diagnosis and response to high-dose radioactive iodine treatment.

Species:
cat

Plain-English summary

An 8-year-old cat diagnosed with thyroid cancer received a single high dose of radioactive iodine treatment. This therapy successfully resolved the cat's hyperthyroidism and led to a significant improvement in its health. Out of eight cases treated, six cats showed complete recovery and lived much longer than expected, with survival times ranging from about six months to over six years. This treatment is considered safe and effective for cats with thyroid cancer, offering a good prognosis for those who respond well.

People also search for: cat thyroid cancer treatment · radioactive iodine for cats · hyperthyroidism in cats symptoms

Abstract

This study reports the scintigraphy, histopathology, sole treatment with high-dose radioactive iodine and outcome of eight cases of feline thyroid carcinoma. Scintigraphic findings were variable and in 7/8 cases scintigraphic features could not reliably distinguish whether the thyroid tissue was malignant. Histopathology revealed typical criteria of malignancy in all cases, with mitotic activity described most frequently (7/8 cases), followed by infiltration of local tissues (4/8 cases). Cellular pleomorphism was infrequently observed. Single high-dose (1100MBq I(131)) radioiodine therapy was successful in 6/8 cases, with complete resolution of hyperthyroidism, and was associated with prolonged survival times (181-2381 days). Sole treatment with high-dose radioiodine is a safe and effective treatment for functional thyroid carcinoma. The prognosis for feline thyroid carcinoma successfully treated with radioiodine is good, with extended survival times commonly achieved.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18835538/