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Peer-reviewed veterinary case report

Fibrodysplasia ossificans progressiva causing muscle hardening

By Yabuzoe, Atsushi et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Internal Medicine, Japan·View original on PubMed

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Original publication title: Fibrodysplasia ossificans progressiva in a Maine Coon cat with prominent ossification in dorsal muscle.

Species:
cat

Plain-English summary

A 1.5-year-old female Maine Coon cat was brought in for skin problems and hard lumps along her spine that had been developing for seven months. X-rays and CT scans showed unusual calcifications in her spine and other areas of her body. A muscle biopsy revealed that her muscle tissue was turning into bone, leading to a diagnosis of fibrodysplasia ossificans progressiva (FOP), a rare condition. Unfortunately, this condition is progressive, and while treatment options are limited, managing symptoms and monitoring her health will be important.

People also search for: Maine Coon cat skin problems · cat muscle calcification · fibrodysplasia ossificans progressiva treatment

Abstract

A one-year and six-month-old female Maine Coon cat presented with skin problems and paravertebral induration with a history of seven months. Survey radiographs and computed tomography revealed prominent calcifications in both sides of cervical, thoracic and lumbar vertebrae and soft tissue in femoral regions, below knee regions and in brachial regions. Histopathological findings from muscle biopsy samples showed connective tissue proliferation around adjacent skeletal muscle, cartilage formation and endochondral ossification. On the basis of these findings, this feline patient was diagnosed with fibrodysplasia ossificans progressiva (FOP). The most prominent signs observed in this FOP case were significant calcifications of dorsal muscle and presentation of cutaneous signs at the early stage.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20046034/