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Peer-reviewed veterinary case report

Cat with progressive muscle stiffness and bone growth disorder

By Valentine, B A et al.·Published in Journal of veterinary internal medicine·1992·Department of Pathology, United States·View original on PubMed

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Original publication title: Fibrodysplasia ossificans progressiva in the cat. A case report.

Species:
cat

Plain-English summary

A 5-year-old male domestic shorthair cat was brought in because he was having trouble walking and seemed increasingly stiff. Within a few weeks, his condition worsened, leading to severe disability. X-rays showed unusual mineral deposits in his muscles, indicating a rare condition called fibrodysplasia ossificans progressiva, which causes muscle tissue to turn into bone. Unfortunately, this condition is progressive and can lead to significant mobility issues. Treatment options are limited, but supportive care can help manage symptoms.

People also search for: cat walking problems · cat stiffness treatment · fibrodysplasia ossificans progressiva in cats

Abstract

Clinical, radiographic, electromyographic, and pathologic findings in a cat with fibrodysplasia ossificans progressiva are described. The features of five previously reported cases of this feline disorder are also presented. This disorder affects young adult to middle-aged cats of both sexes. Characteristic clinical features include progressive stiffness of gait, with enlargement of proximal limb musculature. Radiography reveals multiple mineralized densities within the affected musculature. The clinical course is rapid, with development of severe disability within 2 weeks to several months. Electromyographic and pathologic findings suggest that this is a disorder of connective tissue, affecting primarily the epimysium, tendons, and fasciae, and results in marked proliferation of fibrovascular connective tissue, with associated chondroid and osseous metaplasia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1484375/