Peer-reviewed veterinary case report
Fibropapilloma of the glans penis in a horse.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2008
- Authors:
- Gardiner, David W et al.
- Affiliation:
- Colorado State University Veterinary Diagnostic Laboratory · United States
- Species:
- horse
Plain-English summary
An 18-year-old Arabian stallion was brought to the vet because he was having trouble urinating. During the exam, the vet found several smooth, grayish-pink lumps around the opening of the penis. To treat this, the vet performed a partial amputation of the penis and sent the tissue for further testing. The results showed that the lumps were fibropapillomas, which are benign growths that can occur in this area, and they did not show signs of being a more serious condition called a sarcoid. The treatment was successful in removing the growths.
Abstract
An 18-year-old Arabian stallion was presented for recent onset of stranguria. Physical examination of the distal portion of the glans penis revealed multiple, smooth, glistening, grayish-pink, variably sized, exophytic, nodular masses circumferentially surrounding the external urethral orifice. Partial penile amputation was performed, and the entire specimen was submitted for histological evaluation. Microscopically, the masses consisted of abundant amounts of loosely arranged fibrovascular stroma with low numbers of spindloid to stellate fibrocytes. The overlying epithelium was mildly to moderately hyperplastic with short anastomosing rete ridges (pseudoepitheliomatous hyperplasia). The lesion was diagnosed as fibropapilloma because of features similar to bovine penile fibropapilloma including anatomical location, gross appearance, and histological characteristics. A sarcoid was considered but negated as the lesion lacked the classical streaming and interlacing spindle cell population, "picket-fence" appearance at the epithelial interface, and long, thin, dissecting rete ridges typical of most equine sarcoids. Polymerase chain reaction for the Bovine papillomavirus-1 and Bovine papillomavirus-2 E5 gene and for Equine herpesvirus 1, 3, and 4 was negative on formalin-fixed tissue specimens.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18987237/