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Peer-reviewed veterinary case report

Chronic vomiting and diarrhea from intestinal muscle scarring

By Johnson, C S et al.·Published in Veterinary pathology·2007·Department of Veterinary Pathology, United States·View original on PubMed

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Original publication title: Fibrosing gastrointestinal leiomyositis as a cause of chronic intestinal pseudo-obstruction in an 8-month-old dog.

Species:
dog

Plain-English summary

An 8-month-old female mixed-breed dog was brought to the vet with a month-long history of vomiting and diarrhea. Despite surgery to explore her abdomen, her condition didn't improve, and she was sadly euthanized. A post-mortem examination revealed that her intestines were severely distended and filled with fluid, and the muscle layers of her intestines were replaced by fibrous tissue, indicating a serious condition called fibrosing gastrointestinal leiomyositis. This condition also affected her urinary bladder and stomach, which contributed to her symptoms.

People also search for: dog vomiting and diarrhea · chronic intestinal issues in dogs · fibrosing gastrointestinal leiomyositis in dogs

Abstract

An 8-month-old, female, mixed-breed dog presented to the Iowa State University Veterinary Teaching Hospital with a 1-month history of vomiting and diarrhea. An exploratory laparotomy was performed revealing markedly distended and fluid-filled small and large intestines that were not obstructed. The clinical condition of the dog did not improve subsequent to exploratory surgery, and it was euthanized. At necropsy, both the small and large intestines were distended (approximately 4 cm in diameter) and fluid-filled, and the wall was thin. The abdominal cavity contained approximately 500 ml of a brownish clear fluid. Microscopic lesions of the intestines were confined to the intestinal tunica muscularis and muscularis mucosae and consisted of locally extensive-to-diffuse replacement of the smooth muscle by fibrous tissue and multifocal infiltration by a moderately dense mononuclear inflammatory infiltrate. A unique finding was the presence of similar microscopic lesions in the tunica muscularis of the urinary bladder and stomach.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17197634/