Peer-reviewed veterinary case report
Emodepside/praziquantel spot-on kills worms in cats safely
By Altreuther, G et al.·Published in Parasitology research·2005·Bayer HealthCare AG, Germany·View original on PubMed →
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Original publication title: Field evaluation of the efficacy and safety of emodepside/praziquantel spot-on solution against naturally acquired nematode and cestode infections in domestic cats.
- Species:
- cat
Plain-English summary
A group of cats with intestinal worm infections were treated with a spot-on solution containing emodepside and praziquantel to see how well it worked. The treatment showed over 98% effectiveness in reducing worm eggs in their feces, and it completely eliminated tapeworm segments. In comparison, a control treatment with selamectin also worked well but was slightly less effective. The cats experienced no serious side effects, making this spot-on treatment a safe and effective option for treating these common infections.
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Abstract
Two controlled, blinded and randomized multi-site clinical field studies evaluated the efficacy and safety of emodepside/praziquantel spot-on in the treatment of gastrointestinal nematode and cestode infections in cats. In a study conducted in Europe, faecal egg count reductions of >98% for all nematode eggs and eggs of Toxocara cati, respectively, were observed in cats treated with emodepside/praziquantel spot-on (Profender, Bayer AG, Leverkusen, Germany). For a positive-control product containing selamectin (Stronghold) reductions of >95% were observed. A 100% reduction of faecal eggs and proglottids was observed in cats treated with emodepside/praziquantel spot-on that were infected with cestodes. In a study conducted in North America, cats were treated with either emodepside/praziquantel spot-on plus a placebo tablet or a combination of two control products containing, respectively, selamectin (Revolution) and epsiprantel (Cestex). Faecal egg count reduction for eggs of T. cati was >99% for both treatments. For faecal eggs and proglottids of Dipylidium caninum reductions of >99 and >97% were recorded for cats treated with emodepside/praziquantel spot-on and the control group, respectively. No adverse reactions were observed in the European study, and only mild ones of short duration in a few cats from both treatment groups of the North American study. The two studies demonstrated that emodepside/praziquantel spot-on is highly efficacious and safe under field conditions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16228276/