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Peer-reviewed veterinary case report

Ultrasound with Sonazoid shows rare benign liver tumor like cancer

By Tamura, Masahiro et al.Ā·Published in The Journal of veterinary medical scienceĀ·2019Ā·Department of Veterinary Clinical Sciences, JapanĀ·View original on PubMed →

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Original publication title: Findings of contrast-enhanced ultrasonography with Sonazoid for cholangiocellular adenoma in three dogs.

Species:
dog

Plain-English summary

Three dogs were diagnosed with a rare type of liver tumor called cholangiocellular adenoma, which is usually benign. When veterinarians used a special imaging technique called contrast-enhanced ultrasonography (CEUS) with a contrast agent named Sonazoid, the results looked similar to those of malignant tumors. This can make it tricky to identify the tumor type just by looking at the images. The study highlights the importance of using CEUS to help differentiate between benign and malignant liver lesions in dogs, but it also shows that benign tumors can sometimes appear concerning on imaging tests.

People also search for: dog liver tumor symptoms Ā· cholangiocellular adenoma in dogs Ā· contrast ultrasound for dog liver issues

Abstract

Contrast-enhanced ultrasonography (CEUS) is useful to distinguish benign and malignant focal liver lesions in dogs. Cholangiocellular adenoma is an extremely rare benign tumor in dogs and has not been examined using CEUS with Sonazoid. The aim of this study was to describe findings of CEUS with Sonazoid in three dogs with cholangiocellular adenoma. All three dogs showed contrast defects in the Kupffer phase and these findings mimicked malignant neoplasia during the Kupffer phase. Moreover, all dogs showed early washout and hypoechoic lesions relative to the surrounding normal liver parenchyma in the portal phase. To our knowledge, this is the first study to report that CEUS findings of cholangiocellular adenoma with Sonazoid mimicked malignancy in three dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31243194/