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Peer-reviewed veterinary case report

Firocoxib prevents urate joint pain and lameness in dogs

By Drag, Marlene et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2007·Merial Limited, United States·View original on PubMed

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Original publication title: Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs.

Species:
dog

Plain-English summary

A group of dogs with joint pain caused by urate crystals was treated with firocoxib, a common anti-inflammatory medication, to see if it could help reduce their lameness. The study compared firocoxib to other pain medications like carprofen, deracoxib, and meloxicam. While all medications were tested, only the dogs receiving firocoxib did not show significant lameness at the peak of their symptoms. This suggests that firocoxib may be effective in managing pain and inflammation related to urate-induced joint issues in dogs.

People also search for: dog joint pain treatment · firocoxib for dogs · urate crystals in dogs · dog lameness medication

Abstract

This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness. Lameness scoring and force plate gait analysis were used to assess efficacy. The resulting lameness scores and force plate ground reaction forces after urate crystal injection were not significantly different among the groups. Relative to each group's baseline (nonlame) score, only the firocoxib group was not significantly lame, based on lameness score, at the model's peak effect.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17447224/