Peer-reviewed veterinary case report
Fatal brain infection in 10-year-old horse from Halicephalobus
By Avila, V A et al.·Published in Veterinary parasitology, regional studies and reports·2020·Departamento de Patologí·View original on PubMed →
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Original publication title: First case of fatal equine meningoencephalitis caused by Halicephalobus gingivalis in Mexico.
- Species:
- horse
Plain-English summary
A 10-year-old Andalusian horse showed signs of severe illness, including difficulty swallowing, fever, weakness, and unsteady movements. Unfortunately, the horse passed away despite medical attention. A post-mortem examination revealed inflammation in the brain and the presence of a soil nematode called Halicephalobus gingivalis, which is known to cause fatal brain infections in horses. This case marks the first confirmed instance of this particular nematode affecting horses in Mexico.
People also search for: horse brain infection symptoms · equine meningoencephalitis causes · Halicephalobus gingivalis in horses
Abstract
Aberrant nematode larval migration in the CNS of horses is rare but frequently fatal; one of the main etiological agents involved in this illness is Halicephalobus gingivalis. This soil nematode has been associated with several fatal equine meningoencephalitis reports worldwide; however, it had never been diagnosed in horses of Mexico. A 10 year-old Andalusian horse presented dysphagia, fever, weakness, prostration and ataxia; the patient expired during the medical attention. Post mortem examination was performed and no gross alterations were found. Histopathology revealed meningoencephalitis, vasculitis and intralesional adult nematodes, larvae and eggs compatible with Halicephalobus spp. A polymerase chain reaction (PCR) for the nuclear large subunit ribosomal RNA gene (LSU rDNA) of nematodes was performed from formalin-fixed and paraffin wax-embedded sections of brain. Posterior nucleotide sequence analysis of the amplified fragment identified the agent as H. gingivalis. To our knowledge, this is the first confirmed report of Halicephalobiasis in Mexico.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32448540/