Peer-reviewed veterinary case report
Cat with systemic Cryptococcus albidus infection after prednisone
By Kano, Rui et al.·Published in Medical mycology·2008·Department of Pathobiology, Japan·View original on PubMed →
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Original publication title: First case of feline systemic Cryptococcus albidus infection.
- Species:
- cat
Plain-English summary
A cat with hind leg paralysis was diagnosed with a serious infection caused by a type of yeast called Cryptococcus albidus. The cat had been treated with prednisone for a month before showing symptoms, and tests revealed the presence of the yeast in its lymph nodes and cerebrospinal fluid. Unfortunately, despite being treated with voriconazole, the cat passed away after three days. This case highlights the importance of considering Cryptococcus albidus as a possible cause of illness in cats.
People also search for: cat hind leg paralysis · Cryptococcus infection in cats · voriconazole treatment for cat infection
Abstract
This paper, as best as the authors can determine, is the first to describe a documented case of systemic infection caused by Cryptococcus albidus in a cat. The patient had a history of paralysis of the hind legs and had been treated with prednisone for 1 month. Microscopic examination of a fine needle biopsy specimen from a right popliteal lymph node showed granulomatous inflammation with many encapsulated yeast cells. Moreover, microscopic examination of Indian ink preparations of the cerebrospinal fluid revealed encapsulated ovoid yeast cells. Thus this case was diagnosed to be cryptococcosis. However, the cat died after treatment for three days with voriconazole. Isolates recovered from samples of the cerebrospinal fluid, liver and spleen were identified as C. albidus by molecular analysis, as well as through morphologic and biochemical studies. Therefore, this case indicates that C. albidus should be considered as a potential feline pathogen.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17885946/