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Peer-reviewed veterinary case report

First case report of Sarcocystis neurona-induced equine protozoal myeloencephalitis in Japan.

Journal:
The Journal of veterinary medical science
Year:
2003
Authors:
Katayama, Yoshinari et al.
Affiliation:
Equine Research Institute · Japan
Species:
horse

Plain-English summary

A three-year-old male Thoroughbred racehorse from the United States developed a serious condition called equine protozoal myeloencephalitis, which is caused by a parasite known as Sarcocystis neurona. Five days after showing signs of unsteady movement (ataxia), the horse became very weak and unable to stand (astasia). Tests revealed inflammation and bleeding in the spinal cord, and specific antibodies to the parasite were found in both the horse's blood and spinal fluid. This case is significant as it marks the first reported instance of this disease in Japan.

Abstract

Equine protozoal myeloencephalitis developed in a three-year-old male Thoroughbred racehorse imported from the United States. The animal showed astasia five days after the onset of ataxia. Histopathologically, focal nonpurulent myelitis accompanied by hemorrhage and perivascular infiltration was observed in the fourth and fifth cervical spinal cord. Immunohistochemically, shizonts were occasionally observed and were positive for anti-Sarcocystis neurona (S. neurona) antiserum. S. neurona-specific antibodies were detected in the serum and cerebrospinal fluid by Western blot. This is the first equine protozoal myeloencephalitis case in Japan.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/12867742/