Peer-reviewed veterinary case report
Female dog with scrotal testicles and 78,XX sex disorder
By Del Carro, A P et al.·Published in Reproduction in domestic animals = Zuchthygiene·2014·Université, France·View original on PubMed →
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Original publication title: First description of scrotal testicles in a dog affected by 78, XX testicular disorder of sex development.
- Species:
- dog
Plain-English summary
An eight-month-old female dog was brought in because she had unusual external genitalia. After a thorough examination and imaging tests, the vet found that she had two testicles in the normal scrotal position, which is rare for her condition. This condition, known as a 78,XX testicular disorder of sex development, means there was a mismatch between her chromosomes and her reproductive organs. This case is unique because most similar cases report the testicles being undescended (cryptorchid).
People also search for: dog ambiguous genitalia · female dog with testicles · 78 XX testicular disorder in dogs · dog sex development issues
Abstract
An eight-month-old female dog presented with ambiguous external genitalia. A thorough clinical examination together with various imaging techniques and a histology examination showed the presence of two testicles linked to both the Mullerian and Wolffian ducts. The discovery of the 78,XX SRY-negative karyotype led to the diagnosis of incoherence between the chromosomal and gonadal sex, which is typical for a 78,XX testicular disorder of sex development. Our case was unique because the testicles were still located in their normal scrotal position, whereas the literature contains reports of the presence of cryptorchid testicles in this karyotype setting. To our knowledge, this is the first case that describes an SRY-negative 78,XX testicular disorder of sex development with bilateral scrotal testicles.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25131568/