Peer-reviewed veterinary case report
First detection of the equine herpesvirus 1 neuropathogenic variant in Brazil.
- Journal:
- Revue scientifique et technique (International Office of Epizootics)
- Year:
- 2011
- Authors:
- Mori, E et al.
- Affiliation:
- Department of Preventive Veterinary Medicine and Animal Health · Brazil
- Species:
- horse
Plain-English summary
This report talks about the first time a specific dangerous strain of equine herpesvirus 1 (EHV-1) was found in Brazil, which caused a serious illness called equine herpesvirus myeloencephalopathy (EHM) in a mare. Genetic testing showed that this strain is different from two other strains found in Brazil that are not known to cause severe disease. The researchers believe that there may be other unknown factors that contribute to how this virus causes serious problems in horses. This discovery helps improve our understanding of EHV-1 infections in Brazil.
Abstract
This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G2254/D752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A2254/N752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22435205/