Peer-reviewed veterinary case report
First report of canine parvovirus type 2 and CPV2c in Chilean puppies
By Castillo, Cristobal et al.·Published in Frontiers in veterinary science·2020·Departamento de Patologí·View original on PubMed →
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Original publication title: First Molecular Identification of Canine Parvovirus Type 2 (CPV2) in Chile Reveals High Occurrence of CPV2c Antigenic Variant.
- Species:
- dog
Plain-English summary
A group of puppies in Chile with severe diarrhea and vomiting were tested for canine parvovirus type 2 (CPV2), a serious intestinal virus. Out of 65 samples, 30 tested positive for the virus, with the majority identified as the CPV2c variant. This study highlights the presence of CPV2c in the region, which is important for understanding and managing outbreaks. If your puppy shows signs of severe gastroenteritis, it's crucial to consult your veterinarian for testing and treatment options.
People also search for: puppy vomiting treatment · dog diarrhea causes · canine parvovirus symptoms
Abstract
Canine parvovirus type 2 (CPV2) is one of the most important intestinal pathogens in dogs and puppies. CPV2 has been evolved into three genetic and antigenic variants (2a, 2b, and 2c), which are distributed worldwide. We reported the first study of genetic diversity of CPV2 in Chile. Sixty-five samples were collected from puppies presenting with severe gastroenteritis and different vaccination statuses. PCR, restriction fragment length polymorphism (RFLP), and partial sequencing of the coding region of the structural viral protein VP2 was performed. Thirty of a total of 65 samples tested positive by PCR out of which 19 were further classified as CPV2c and one as CPV2a using RFLP and Sanger sequencing. The phylogeny was in concordance with the RFLP analysis. This is the first report of the genetic characterization of CPV2 in Chile and reveals a high occurrence of CPV2c.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32432131/