Peer-reviewed veterinary case report
First report of praziquantel-resistant tapeworm in a dog in Europe
By Oehm, Andreas W et al.·Published in Parasitology·2024·Institute of Parasitology·View original on PubMed →
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Original publication title: First report of apparent praziquantel resistance inin Europe.
- Species:
- dog
Plain-English summary
A dog imported to Switzerland from Spain was suffering from chronic tapeworm infections and was not responding to praziquantel, a common treatment for this issue. The dog showed mild symptoms like restlessness, difficulty passing stool, and anal itching. After trying different medications without success, the vet finally used mebendazole, which successfully cleared the tapeworms after five days of treatment. The dog's symptoms improved, and follow-up tests showed no signs of infection for 10 months.
People also search for: dog tapeworm treatment · praziquantel resistance in dogs · mebendazole for dog tapeworms
Abstract
is a common tapeworm of dogs. Two cases of praziquantel resistance have been described inin the United States. No further reports have been published to the authors’ knowledge. Here, the case of a dog imported to Switzerland from Spain with a history of chronic excretion of tapeworm proglottids and unresponsiveness to praziquantel treatments is reported. Clinical signs were mild (restlessness, tenesmus, anal pruritus, squashy feces) and flea infestation could be ruled out. Infection withwas confirmed through morphological and genetic parasite identification. Different subsequently applied anthelmintic compounds and protocols, including epsiprantel, did not confer the desired effects. Proglottid shedding only stopped after oral mebendazole administration of 86.2 mg kgbody weight for 5 consecutive days. Clinical signs resolved and the dog remained coproscopically negative during a follow-up period of 10 months after the last treatment. This case represents the first reported apparent praziquantel and epsiprantel resistance inin Europe. Treatment was extremely challenging especially due to the limited availability of efficacious alternative compounds.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38571299/