Peer-reviewed veterinary case report
Adult border collie dog suspected of glycogen storage disease type 1a
By Rolph, K E et al.·Published in The Journal of small animal practice·2022·Clinical Sciences Department and Center for Integrative Mammalian Research·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: First report of suspected glycogen storage disease type 1a occurring in an adult dog.
- Species:
- dog
Plain-English summary
A 4-year-old female border collie was brought to the vet after experiencing a serious internal bleeding issue due to a ruptured liver tumor. Blood tests showed high levels of liver enzymes and other signs that indicated a problem with her liver, specifically glycogen storage disease type 1a, which is a condition where the liver can't properly break down sugar. Unfortunately, this case is notable because it's the first time this disease has been suspected in an adult dog. The dog’s condition highlights the importance of thorough testing when unusual symptoms arise.
People also search for: border collie liver disease · dog internal bleeding causes · glycogen storage disease in dogs
Abstract
A 4-year-old female border collie was presented with haemoabdomen following the rupture of a hepatocellular carcinoma. After referral for ongoing elevation of alanine aminotransferase and alkaline phosphatase, the dog was found to have marked vacuolar hepatopathy due to glycogen accumulation within the liver, fasting hypoglycaemia and hyperlactataemia, and a negative response to glucagon stimulation testing. These changes were strongly suggestive of glycogen storage disease type 1a. Based on our literature search, this report documents the first adult canine to be diagnosed with suspected glycogen storage disease type 1a.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35272391/