Peer-reviewed veterinary case report
Cat with brain and urinary fungal infection treated successfully
By Gonzalez, Juan F et al.·Published in Journal of feline medicine and surgery·2010·Facultad de Medicina Veterinaria·View original on PubMed →
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Original publication title: First report on the diagnosis and treatment of encephalic and urinary paracoccidioidomycosis in a cat.
- Species:
- cat
Plain-English summary
A male Persian cat was brought to the vet with a persistent fever, lack of appetite, weakness, and unusual eye movements. Tests showed he had a serious fungal infection affecting both his brain and urinary system. The vet treated him with oral fluconazole, which helped control his neurological symptoms, and used a special antifungal medication to clear the infection from his urine. Unfortunately, after five years of treatment, the cat developed severe kidney problems and had to be euthanized.
People also search for: cat fever and weakness · cat fungal infection treatment · Persian cat kidney problems · cat nystagmus causes · fluconazole for cats
Abstract
A male Persian cat was presented with persistent fever, anorexia, weakness, hypopyon, nystagmus, and intention tremors. The hemogram showed severe neutropenia and laboratory analysis on cerebrospinal fluid (CSF) smears revealed abundant yeast cells compatible with Paracoccidioides brasiliensis. Urinalysis demonstrated persistent funguria and an increased urine protein-to-creatinine ratio (UPC) in addition to mild azotemia. Long-term therapy with oral fluconazole was effective in controlling the nervous system signs. Funguria was resolved with subcutaneous administration of diluted amphotericin B in a large volume of saline solution for a period of 12 weeks during the second year after initial diagnosis. Throughout 5 years of treatment, no adverse effects were observed and tolerance to the drugs was normal. Due to development of progressive uremic syndrome the animal was euthanased. To the best of our knowledge, this report is the first clinical case described of a nervous and urinary system infection caused by the P brasiliensis in a cat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20471880/