Peer-reviewed veterinary case report
Flexible low-cost system for small animal aerosol inhalation exposure to drugs, proteins, inflammatory agents, and infectious agents.
- Journal:
- BioTechniques
- Year:
- 2009
- Authors:
- Schroeder, William G et al.
- Affiliation:
- Department of Microbiology · United States
- Species:
- rodent
Abstract
The design for a simple, low-cost aerosol generation system for rodent inhalation studies is described here. This system is appropriate for low biohazard-level agents. In this study, two biosafety level 2 agents, Pasturella pneumotropica and Pseudomonas aeruginosa, were tested successfully. This system was also used to immunize mice and guinea pigs in ovalbumin-based models of pulmonary inflammation. This design is appropriate for studies with limited budgets and lower-level biosafety containment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19317668/