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Peer-reviewed veterinary case report

Flow Cytometry in the Diagnosis of Canine B-Cell Lymphoma

Journal:
Frontiers in Veterinary Science
Year:
2021
Authors:
Fulvio Riondato & Stefano Comazzi
Affiliation:
Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Grugliasco, Italy · CH
Species:
dog

Abstract

B cell lymphoma (BCL) is a heterogeneous group of lymphoid malignancies which comprise the majority of canine lymphomas. Diffuse large B cell lymphoma is the most common lymphoma subtype in dogs but other subtypes (e.g., marginal zone lymphoma, follicular lymphoma, mantle cell lymphoma, and others) have been described. This review aims to explore the use of flow cytometry to refine the diagnosis of canine BCL. Particular emphasis will be given to the possible identification of peculiar immunotypes, putative prognostic markers, staging and minimal residual disease.

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Original publication: https://doi.org/10.3389/fvets.2021.600986