Peer-reviewed veterinary case report
Fluorenone alkaloid from Caulophyllum robustum Maxim. with anti-myocardial ischemia activity.
- Journal:
- Archives of pharmacal research
- Year:
- 2009
- Authors:
- Wang, Sicen et al.
- Affiliation:
- School of Medicine · China
Abstract
A new fluorenone alkaloid (caulophine) was isolated from the radix of Caulophyllum robustum Maxim. (collected from the Qinling mountains) using cell membrane chromatography as the screening method. Caulophine was identified as 3-(2-(dimethylamino)ethyl)-4,5-dihydroxy-1,6-dimethoxy-9H-fluoren-9-one based on physicochemic and spectroscopic analyses, particularly by NMR spectroscopic data (i.e., COSY, HMQC, HMBC, NOESY). Caulophine possessed anti-myocardial ischemia activity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19407969/