Peer-reviewed veterinary case report
Two dogs died after flurazepam poisoning and detection in urine
By Beier, E & Bischoff, KĀ·Published in Veterinary and human toxicologyĀ·1997Ā·College of Veterinary Medicine, United StatesĀ·View original on PubMed ā
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Original publication title: Flurazepam toxicosis in two dogs.
- Species:
- dog
Plain-English summary
Two dogs were brought in after being poisoned with flurazepam, a medication typically used for sleep disorders. Unfortunately, both dogs died from the effects of the poisoning. One dog's urine tested positive for flurazepam, confirming the cause of the toxicosis. Flumazenil, a drug that can reverse the effects of benzodiazepine poisoning, is being considered for use in pets, although it was not used in these cases.
People also search for: dog poisoning symptoms Ā· flurazepam effects on dogs Ā· flumazenil for dog overdose
Abstract
Flurazepam is a benzodiazepine (BZD) derivative and a category IV controlled substance. It is a widely prescribed hypnotic drug for use in sleep disorders. Two dogs were maliciously poisoned with this drug and died. Flurazepam was detected in the urine of 1 dog by thin-layer chromatography. Flumazenil, an antagonist for BZD receptors, is currently used in humans to reverse the effects of intoxication with BZD. It may also be of use in treating companion animals.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9397505/