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Peer-reviewed veterinary case report

Weimaraner with foot sinus tracts healed by ciclosporin

By Oliveira, A M et al.Ā·Published in The Journal of small animal practiceĀ·2007Ā·University of Edinburgh, United KingdomĀ·View original on PubMed →

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Original publication title: Focal metatarsal sinus tracts in a Weimaraner successfully managed with ciclosporin.

Skin & coat

Plain-English summary

A 6-year-old male Weimaraner was brought in for two swollen areas on the bottom of his back feet that had been present for five months. The areas were slightly soft and oozed a reddish fluid when pressed. Tests showed that the discharge was inflamed but did not contain any bacteria. The vet treated the dog with ciclosporin, which completely cleared up the problem, but when the dose was lowered, the symptoms returned. Increasing the dose again led to another successful recovery.

People also search for: Weimaraner foot swelling treatment Ā· dog sinus tracts Ā· ciclosporin for dogs Ā· dog skin inflammation remedies

Abstract

Focal metatarsal sinus tracts ('fistulation') are, to the authors knowledge, reported for the first time in a Weimaraner. The six-year-old, entire male had a five-month history of two symmetrical, well-demarcated sinuses on the plantar aspect of each metatarsus. The area surrounding each pair of sinuses was slightly fluctuant and a serosanguineous discharge could be expressed. Cytological examination of the discharge was characteristic of pyogranulomatous inflammation. Bacterial culture showed the material to be sterile. Examination of a skin biopsy revealed a severe inflammatory reaction involving the dermal collagen, with an infiltrate of neutrophils, macrophages, lymphocytes, plasma cells and multi-nucleated giant cells, with some micro-pustule formation. Treatment with ciclosporin induced total remission. Reduction of the dose of ciclosporin resulted in recurrence of the physical signs with further remission on re-introduction of the original dosage. This is the first report of the use of ciclosporin to control this condition.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17355608/