Peer-reviewed veterinary case report
Cat with lung fungal granuloma from Cladophialophora bantiana
By Evans, Natashia et al.·Published in Medical mycology·2011·Faculty of Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: Focal pulmonary granuloma caused by Cladophialophora bantiana in a domestic short haired cat.
- Species:
- cat
Plain-English summary
A 12-year-old domestic short-haired cat was coughing for four weeks before being diagnosed with a lung mass caused by a type of fungus called Cladophialophora bantiana. X-rays showed a problem in the right lung, and tests confirmed a fungal infection. The cat underwent surgery to remove the affected lung tissue and was treated with antifungal medications for several months. Unfortunately, the cat was later euthanized due to unrelated liver cancer, but there were no signs of the fungal infection returning.
People also search for: cat coughing treatment · lung infection in cats · Cladophialophora bantiana in cats · antifungal treatment for cats
Abstract
Following a 4-week history of coughing, a 12-year-old cat with a history of insulin-dependent diabetes mellitus was diagnosed with a pulmonary granuloma caused by Cladophialophora bantiana. Thoracic radiographs revealed consolidation of the right caudal lung lobe and cytology confirmed the presence of mycotic pneumonia. Results of clinical investigations showed no evidence of extra-pulmonary infection. A thoracotomy and lung lobe resection was performed. Histological examination of the mass revealed black pigmented fungal hyphae and pyogranulomatous inflammation. Cultures inoculated with portions of these tissues yielded a dark walled fungus consistent with an etiologic agent of phaeohyphomycosis and DNA sequencing confirmed the presence of Cladophialophora bantiana. The cat was treated with itraconazole for 4 weeks post-operatively and then with posaconazole for 7 months but was euthanized 13 months after initial diagnosis due to a hepatocellular carcinoma. On post-mortem examination there was no evidence of recurrent fungal infection. This is the first report of localized pulmonary C. bantiana infection in a cat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20854228/