Peer-reviewed veterinary case report
Dog thyroid cancer with bone and cartilage growth in tumor stroma
By Kobayashi, Ryosuke et al.·Published in The Journal of veterinary medical science·2014·Pathology Department, Japan·View original on PubMed →
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Original publication title: Follicular thyroid carcinoma characterized by abundant stromal components with chondroid and osseous metaplasia in a dog.
- Species:
- dog
Plain-English summary
A dog developed a noticeable mass in its neck, which was confirmed through a CT scan to be surrounding the trachea and associated with some lung masses. Tests showed that the mass was a type of cancer called follicular thyroid carcinoma, characterized by abnormal growth of thyroid cells and unusual supportive tissue that included cartilage and bone. Fortunately, there was no invasion into surrounding tissues. This case highlights a unique presentation of thyroid cancer in dogs, and while it can be serious, early diagnosis is key for treatment options.
People also search for: dog neck mass · thyroid cancer in dogs · dog cervical mass treatment
Abstract
A dog developed a cervical mass, and computed tomography verified a mass surrounding the trachea with some pulmonary masses. Histopathologically, the cervical mass was composed of malignant neoplastic cells showing follicular appearance which reacted positive for thyroglobulin on immunohistochemistry. A characteristic feature of the tumor was abundant and metaplastic stromal components. Anastomosed collagenous tissues connecting to capsule of the tumor were abundant in the stroma. In parts of the collagenous tissues, mature cartilages and bones were continuously formed. There was no cellular atypia or invasion in the components. We diagnosed this case as follicular thyroid carcinoma with metaplastic stroma. This is the first case report that characterizes stromal components with chondroid and osseous metaplasia in a canine thyroid carcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24805905/