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Peer-reviewed veterinary case report

Follow-up on dogs and cats with silent Cryptococcus gattii infection

By Duncan, C et al.·Published in Medical mycology·2005·Department of LACS, Canada·View original on PubMed

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Original publication title: Follow-up study of dogs and cats with asymptomatic Cryptococcus gattii infection or nasal colonization.

Species:
cat

Plain-English summary

A group of five dogs and seven cats were found to have a fungal infection called Cryptococcus gattii, but most showed no symptoms. Over the next few months, two of the cats developed health issues related to the infection, while the others remained healthy but continued to test positive for the fungus. This suggests that some pets can carry the infection without showing signs, but there is a risk that they could become sick later. It's important for pet owners to monitor their animals and consult with their vet if they have concerns about fungal infections.

People also search for: dog nasal infection treatment · cat fungal infection symptoms · Cryptococcus gattii in pets

Abstract

The pathogenesis of Cryptococcus spp. infection following nasal colonization is unclear. This article reports follow-up data on a cohort of seven cats and five dogs identified in a previous study as sub-clinically infected with Cryptococcus spp. or colonized by C. gattii. Two cats progressed to clinical disease within four to six months of initial detection of antigenemia and nasal cavity colonization. The ten other animals remained asymptomatic but many were repeatedly positive on cryptococcal antigen testing or nasal fungal culture suggesting protracted infection or colonization. The results indicate that asymptomatically infected animals may clear the organism, remain sub-clinically infected or progress to clinical disease. Factors influencing the transition from exposure to disease require further investigation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16396253/