Peer-reviewed veterinary case report
Foot-and-mouth disease virus 3C protease: recent structural and functional insights into an antiviral target.
- Journal:
- The international journal of biochemistry & cell biology
- Year:
- 2007
- Authors:
- Curry, Stephen et al.
- Affiliation:
- Imperial College · United Kingdom
Abstract
The 3C protease from foot-and-mouth disease virus (FMDV 3C(pro)) is critical for viral pathogenesis, having vital roles in both the processing of the polyprotein precursor and RNA replication. Although recent structural and functional studies have revealed new insights into the mechanism and function of the enzyme, key questions remain that must be addressed before the potential of FMDV 3C(pro) as an antiviral drug target can be realised.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16979372/