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Peer-reviewed veterinary case report

Formation and Analysis of Biofilms in Vivo.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2024
Authors:
Wang, Yang & Wang, Yuxin
Affiliation:
College of Animal Science and Technology · China

Abstract

Establishing a biofilm infection model in vivo allows a better understanding of the underlying infection mechanisms of bacteria. Here we describe a method for constructing an in vivo biofilm model of Streptococcus suis. The animal modeled is a piglet, which is the natural reservoir of S. suis, and the mode of clinical infection is simulated by intranasal inoculation of S. suis. This model is in line with clinical practice, easy to operate, and has good repeated stability.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38884908/