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Peer-reviewed veterinary case report

Fosfomycin susceptibility of canine methicillin-resistant Staphylococcus pseudintermedius isolates.

Journal:
Research in veterinary science
Year:
2014
Authors:
DiCicco, Matthew et al.
Affiliation:
School of Engineering · Canada
Species:
dog

Abstract

The effectiveness of fosfomycin was examined across 31 methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains by agar dilution. Prevalence of the fosfomycin-resistance determinant gene, fosB, was assessed by PCR analysis. Results found that 84% of isolates were fosfomycin-susceptible. Interestingly, 87% of isolates possessed fosB, indicating no association between this putative staphylococci resistance gene and phenotypic resistance. Further evaluation of fosfomycin as a potential treatment of MRSP in dogs is warranted.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24569298/