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Peer-reviewed veterinary case report

Four independent molecular prion protein parameters for discriminating new cases of C, L, and h bovine spongiform encephalopathy in cattle.

Journal:
Journal of clinical microbiology
Year:
2011
Authors:
Langeveld, Jan P M et al.
Affiliation:
Central Veterinary Institute of Wageningen UR · Netherlands

Abstract

In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21677067/