Peer-reviewed veterinary case report
Frameless radiosurgery treats brain tumors in 51 dogs
By Mariani, C L et al.·Published in Veterinary and comparative oncology·2015·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Frameless stereotactic radiosurgery for the treatment of primary intracranial tumours in dogs.
- Species:
- dog
Plain-English summary
A group of 51 dogs with various types of brain tumors, including meningiomas and pituitary tumors, underwent a new treatment called frameless stereotactic radiosurgery (SRS). This technique delivers a precise dose of radiation to the tumor while minimizing damage to surrounding tissue. The dogs had a median survival time of about 399 days after treatment, with some experiencing only mild side effects. This method proved to be effective and resulted in fewer complications compared to traditional radiation therapy, making it a promising option for dogs with brain tumors.
People also search for: dog brain tumor treatment · meningioma in dogs · stereotactic radiosurgery for dogs
Abstract
Stereotactic radiosurgery (SRS) is a procedure that delivers a single large radiation dose to a well-defined target. Here, we describe a frameless SRS technique suitable for intracranial targets in canines. Medical records of dogs diagnosed with a primary intracranial tumour by imaging or histopathology that underwent SRS were retrospectively reviewed. Frameless SRS was used successfully to treat tumours in 51 dogs with a variety of head sizes and shapes. Tumours diagnosed included 38 meningiomas, 4 pituitary tumours, 4 trigeminal nerve tumours, 3 gliomas, 1 histiocytic sarcoma and 1 choroid plexus tumour. Median survival time was 399 days for all tumours and for dogs with meningiomas; cause-specific survival was 493 days for both cohorts. Acute grade III central nervous system toxicity (altered mentation) occurred in two dogs. Frameless SRS resulted in survival times comparable to conventional radiation therapy, but with fewer acute adverse effects and only a single anaesthetic episode required for therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24007303/