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Peer-reviewed veterinary case report

Friend or foe? Targeting microglia in Alzheimer's disease.

Journal:
Cytokine
Year:
2016
Authors:
Dhib-Jalbut, Suhayl
Affiliation:
Department of Neurology · United States

Abstract

Inflammation is believed to be a component of a number of degenerative brain diseases including Alzheimer's disease. A recent article by Fu and colleagues (2016) demonstrated that the cytokine IL-33 can modulate microglia in an animal model of AD to become better scavengers of beta-amyloid and less pro-inflammatory. The findings have potential therapeutic implications for a number of brain conditions.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27442003/