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Peer-reviewed veterinary case report

From FUS to Pandora syndrome: where are we, how did we get here, and where to now?

Journal:
Journal of feline medicine and surgery
Year:
2014
Authors:
Tony Buffington, C A et al.
Affiliation:
The Ohio State University College of Veterinary Medicine · United States
Species:
cat

Plain-English summary

Over the past 40 years, our understanding of lower urinary tract signs (LUTS) in cats has changed a lot. It used to be thought that the bladder was always the main problem, but new research suggests that it can also be affected by broader issues related to stress in the body. This article discusses how these findings could change how we diagnose and treat cats with LUTS. The authors also emphasize the importance of veterinarians collaborating to better understand these conditions and potentially reduce how often they occur.

Abstract

UNLABELLED: NEW CONCEPTS: Ideas about the causes of lower urinary tract signs (LUTS) in cats have changed significantly in the past 40 years. Recent research is challenging the conventional view that the bladder is always the perpetrator of LUTS, and suggests that the bladder can also be one victim of a systemic process associated with a sensitized central stress response system. AIM: In this article the authors provide their perspective on the implications of these findings for the diagnosis and treatment of cats with LUTS, provide some historical context, and suggest ways that the veterinary profession might work together to better understand the disorders underlying these signs, and possibly reduce their prevalence.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24794035/