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Peer-reviewed veterinary case report

Fructosamine test for diabetes in dogs and cats

By Reusch, C E et al.·Published in Journal of veterinary internal medicine·1993·Department of Veterinary Internal Medicine, Germany·View original on PubMed

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Original publication title: Fructosamine. A new parameter for diagnosis and metabolic control in diabetic dogs and cats.

Species:
cat

Plain-English summary

A study found that fructosamine levels in the blood can help diagnose and manage diabetes in dogs and cats. For pets with diabetes, high fructosamine levels indicate poor blood sugar control, while normal levels suggest good management. This test is more reliable than just checking blood sugar levels alone, especially for pets on insulin therapy. By using fructosamine testing, veterinarians can better assess how well a diabetic pet is doing and adjust treatment as needed.

People also search for: dog diabetes management · cat diabetes test · fructosamine levels in pets · how to control blood sugar in diabetic dogs · insulin therapy for diabetic cats

Abstract

Fructosamines are glycated serum proteins that, depending on their life span, reflect glycemic control over the previous 2 to 3 weeks. The nitroblue tetrazolium reduction method adapted to auto analysis appeared to be a practical means to assay fructosamine quickly, economically, and accurately. The upper limit of the reference range is 374 mumol/L in dogs (95% percentile) and 340 mumol/L in cats (95% percentile). Newly diagnosed diabetic dogs and cats that had not undergone previous insulin therapy had significantly higher fructosamine concentrations than nondiabetic animals. In diabetic dogs that were receiving insulin therapy, the fructosamine test reflected the glycemic state far more accurately than did individual blood glucose measurements. Animals with satisfactory metabolic control revealed fructosamine concentrations within the reference range, whereas fructosamine concentrations above 400 mumol/L indicated insufficient metabolic control. On the basis of fructosamine concentrations, cats with a transitory hyperglycemia and cats with diabetes mellitus were differentiated. The fructosamine test is a valuable parameter for the diagnosis and metabolic control of diabetes mellitus in dogs and cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8331612/