Peer-reviewed veterinary case report
Full genome sequence of guinea fowl coronavirus associated with fulminating disease.
- Journal:
- Virus genes
- Year:
- 2015
- Authors:
- Ducatez, Mariette F et al.
- Affiliation:
- INRA · France
- Species:
- bird
Abstract
Guinea fowl coronavirus (GfCoV), a recently characterized avian coronavirus, was identified from outbreaks of fulminating disease (peracute enteritis) in guinea fowl in France. The full-length genomic sequence was determined to better understand its genetic relationship with avian coronaviruses. The full-length coding genome sequence was 26,985 nucleotides long with 11 open reading frames and no hemagglutinin-esterase gene: a genome organization identical to that of turkey coronavirus [5' untranslated region (UTR)-replicase (ORFs 1a, 1ab)-spike (S) protein-ORF3 (ORFs 3a, 3b)-small envelop (E or 3c) protein-membrane (M) protein-ORF5 (ORFs 4b, 4c, 5a, 5b)-nucleocapsid (N) protein (ORFs N and 6b)-3' UTR]. This is the first complete genome sequence of a GfCoV and confirms that the new virus belongs to group gammacoronaviruses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25712772/