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Peer-reviewed veterinary case report

Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses.

Journal:
Journal of veterinary science
Year:
2021
Authors:
Kim, Sung Jae et al.
Affiliation:
Department of Veterinary Microbiology · South Korea
Species:
cat

Abstract

Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/33908206/