Peer-reviewed veterinary case report
Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.
- Journal:
- Advanced healthcare materials
- Year:
- 2017
- Authors:
- Pok, Seokwon et al.
- Affiliation:
- Department of Bioengineering · United States
- Species:
- rodent
Abstract
In a rat model of right free wall replacement, the transplantation of an engineered multilayered myocardial patch fabricated from a polycaprolactone membrane supporting a chitosan/heart matrix hydrogel induces significant muscular and vascular remodeling and results in a significantly higher right ventricular ejection fraction compared to use of a commercially available pericardium patch.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28081298/