Peer-reviewed veterinary case report
Functional recovery after the systemic administration of mesenchymal stem cells in a rat model of neonatal hypoxia-ischemia.
- Journal:
- Journal of neurosurgery. Pediatrics
- Year:
- 2018
- Authors:
- Sakai, Takuro et al.
- Affiliation:
- 1Department of Pediatrics.
- Species:
- rodent
Abstract
The authors intravenously infused mesenchymal stem cells (MSCs) into a rat model of neonatal hypoxia-ischemia and found improvements in functional outcome, increased brain volume, and enhanced synaptogenesis. The results of this animal study suggest that the intravenous administration of MSCs should be further explored as a potential treatment for patients suffering from cerebral palsy after hypoxic-ischemic encephalopathy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30074448/