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Peer-reviewed veterinary case report

Ganglion cysts causing lumps near elbow in 4-month-old Afghan Hound

By Cho, K O et al.·Published in Veterinary pathology·2000·View original on PubMed

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Original publication title: Ganglion cysts in a juvenile dog.

Species:
dog
Movement & jointsDogs

Plain-English summary

A 4-month-old male Afghan Hound was brought in with fluid-filled lumps, known as ganglion cysts, around his elbow and hindquarters. After surgery to remove the cysts, they came back twice around the elbow joint, but they did not connect to the joint itself. The cysts were found to be made up of specific types of tissue that can lead to their recurrence. Although the cysts were persistent, the dog was treated surgically, and further management may be needed to address the recurring issue.

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Abstract

Ganglion cysts were diagnosed in a 4-month-old male Afghan Hound. Grossly, the subcutaneous ovoid cysts around the caudal right elbow joint and left ischiatic tuberosity had abundant mucinous fluid and internal folding. The lesions recurred twice around the elbow joint after surgical removal. Neither cyst communicated with the joint cavity. Histologically, the cyst wall consisted of inner myxomatous and outer immature connective tissue. Some parts of the cyst wall had various stages of myxoid metaplasia of collagen tissue leading to new cyst formation. Ultrastructural study revealed that cells in the myxoid metaplastic lesion had well-developed cytoplasmic secretory elements, including abundant rough endoplasmic reticulum, Golgi apparatus, and many smooth-walled vesicles. These ganglion cysts apparently resulted from the metaplasia of fibroblasts to secreting cells.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10896396/