Peer-reviewed veterinary case report
Sensory nerve loss from ganglioradiculitis in a 9-year-old Labrador
By Porter, B et al.·Published in Veterinary pathology·2002·Department of Biomedical Sciences, United States·View original on PubMed →
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Original publication title: Ganglioradiculitis (sensory neuronopathy) in a dog: clinical, morphologic, and immunohistochemical findings.
- Species:
- dog
Plain-English summary
A 9-year-old Labrador Retriever was diagnosed with ganglioradiculitis, a condition that affects the nerves and leads to a significant loss of sensory function. This means the dog may have trouble feeling sensations like touch or pain. The exact cause of this disease is unknown, but it seems to involve the dog's immune system attacking its own nerve cells. Unfortunately, the study does not mention specific treatments or outcomes for this condition, so it's important for pet owners to discuss management options with their veterinarian if they notice similar symptoms in their dog.
People also search for: dog sensory nerve problems · Labrador Retriever nerve disease · ganglioradiculitis treatment in dogs
Abstract
A 9-year-old Labrador Retriever was diagnosed with ganglioradiculitis (sensory neuronopathy). This idiopathic disease of mature dogs is characterized by a profound loss of sensory nerve function due to mononuclear inflammatory infiltration of peripheral ganglia and spinal nerve roots, with destruction of sensory neurons. Immunohistochemistry demonstrates that the infiltrating cells are primarily T lymphocytes and that immunoglobulins are not present on the cell membranes of affected neurons. The pathogenesis of ganglioradiculitis remains unclear, but the evidence points to a cell-mediated immune mechanism.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12243475/