Peer-reviewed veterinary case report
Puppy with stomach lesions from E. coli and distemper infection
By Wada, Y et al.·Published in Veterinary pathology·1996·Kamikawa Livestock Hygiene Service Center, Japan·View original on PubMed →
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Original publication title: Gastric attaching and effacing Escherichia coli lesions in a puppy with naturally occurring enteric colibacillosis and concurrent canine distemper virus infection.
- Species:
- dog
Plain-English summary
A 90-day-old puppy with chronic diarrhea was sadly euthanized due to severe illness. Tests revealed a harmful strain of E. coli bacteria that was damaging the puppy's stomach and intestines, along with signs of a canine distemper virus infection. The bacteria were found both on the surface and inside the cells of the puppy's digestive tract. This case highlights a serious infection that can occur in young dogs, particularly when they are also affected by distemper. Unfortunately, the puppy did not recover, and this situation emphasizes the importance of vaccination and monitoring for signs of illness in young pets.
People also search for: puppy chronic diarrhea treatment · canine distemper virus symptoms · E. coli infection in dogs
Abstract
A puppy suffering from chronic diarrhea was humanely killed at 90 days of age. Numerous Gram-negative bacilli were found adhering to the surface of as well as within epithelial cells from the stomach to the colon. Canine distemper virus inclusions were in the epithelial cytoplasm of the esophageal, gastric, and intestinal mucosa. Typical attaching and effacing ultrastructural lesions were in the stomach, and some bacilli were in the cytoplasm of the epithelial cells. Escherichia coli, isolated from the contents of the small intestine, belonged to serotype 0118: NM and were negative for plasmid-encoded EPEC adherence factor (EAF) and positive for the E. coli attaching effacing (eae) gene. Immunohistologically, bacilli attached to the epithelium from the stomach to the colon were positive for antisera against E. coli 0118. E. coli 0118: NM inoculated into human tissue culture cells (HEp-2 cells) were attached to the surface of the cells and within the cytoplasm. This is the first report of attaching and effacing E. coli (AEEC) infection in the stomach of the dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8952035/