Peer-reviewed veterinary case report
Gastric pleomorphic leiomyosarcoma in a Shetland sheepdog.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2007
- Authors:
- Park, Chun-Ho et al.
- Affiliation:
- Department of Veterinary Pathology · Japan
Abstract
A solitary mass of 6 x 6 x 5 cm was found in the smooth muscle layer of the pyloric part in the stomach of a Shetland sheepdog. The excised mass was solid, gray-white in color, and had central necrosis with hemorrhages. Microscopically, the neoplasm was composed of irregular bundles of spindle-shaped tumor cells and round tumor cells. A few multinucleated cells and gangliocyte-like cells were observed. The nuclei exhibited a high degree of atypia and many cells contained mitotic figures. Immunohistochemically, tumor cells were positive for vimentin and desmin, but negative for c-kit antibody. Ultrastructurally, tumor cells contained cytoplasmic myofilaments and pinocytotic vesicles. Based on these pathological findings, the tumor was diagnosed as gastric pleomorphic leiomyosarcoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17827901/