Peer-reviewed veterinary case report
Gastric muscle tumor found in Shetland sheepdog stomach
By Park, Chun-Ho et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Gastric pleomorphic leiomyosarcoma in a Shetland sheepdog.
Plain-English summary
A Shetland sheepdog was diagnosed with a large tumor in the stomach after showing signs of discomfort. The mass was about the size of a grapefruit and was removed surgically. Upon examination, the tumor was identified as a gastric pleomorphic leiomyosarcoma, which is a type of cancer in the stomach's muscle layer. The dog underwent surgery to remove the tumor, but further details about recovery or additional treatments were not provided.
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Abstract
A solitary mass of 6 x 6 x 5 cm was found in the smooth muscle layer of the pyloric part in the stomach of a Shetland sheepdog. The excised mass was solid, gray-white in color, and had central necrosis with hemorrhages. Microscopically, the neoplasm was composed of irregular bundles of spindle-shaped tumor cells and round tumor cells. A few multinucleated cells and gangliocyte-like cells were observed. The nuclei exhibited a high degree of atypia and many cells contained mitotic figures. Immunohistochemically, tumor cells were positive for vimentin and desmin, but negative for c-kit antibody. Ultrastructurally, tumor cells contained cytoplasmic myofilaments and pinocytotic vesicles. Based on these pathological findings, the tumor was diagnosed as gastric pleomorphic leiomyosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17827901/