Peer-reviewed veterinary case report
Pancreas-specific lipase test normal in dogs with gut blockage
By Luce, Brooke D & Hans, Eric C·Published in Journal of the American Veterinary Medical Association·2022·View original on PubMed →
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Original publication title: Gastrointestinal foreign body obstruction is not associated with abnormal point-of-care pancreas-specific lipase test results in dogs.
- Species:
- dog
Plain-English summary
A group of 50 dogs with stomach issues was tested for a specific enzyme to check for pancreatitis (inflammation of the pancreas) and to see if it was linked to gastrointestinal foreign body obstruction (GIFBO), where something is stuck in the digestive tract. The tests showed that only a small number of dogs had abnormal results, whether or not they had GIFBO, and there was no significant difference between the two groups. Interestingly, older dogs were more likely to have abnormal test results, even without pancreatitis. This suggests that while the test is generally reliable, further imaging is recommended for dogs with unusual results.
People also search for: dog stomach issues · dog pancreatitis test results · gastrointestinal obstruction in dogs · symptoms of foreign body in dog · older dog abnormal enzyme levels
Abstract
OBJECTIVE: To determine the proportion of abnormal results for a point-of-care pancreas-specific lipase assay screening test in dogs lacking clinical evidence of acute pancreatitis with and without gastrointestinal foreign body obstruction (GIFBO). ANIMALS: 50 client-owned dogs with acute abdomen syndrome between April 2019 and January 2021. PROCEDURES: In this prospective observational cohort study, dogs were enrolled into a control non-GIFBO group (n = 25) or GIFBO group (25) on the basis of clinical diagnostics performed at presentation. Dogs with evidence of pancreatitis were excluded. Data collected included signalment, body weight, clinical signs, hematologic test results, abdominal imaging findings, and intraoperative findings. SNAP canine pancreatic lipase (cPL) tests were performed for all dogs within 24 hours of presentation and prior to any surgical procedure. Results were analyzed across all dogs for any clinical associations. RESULTS: The proportions of abnormal SNAP cPL test results in the GIFBO and non-GIFBO groups were 12% (3/25) and 16% (4/25), respectively, with no significant difference. The only differences between groups were that GIFBO canines were more likely to be male (P = 0.02) and had a slightly longer duration of clinical signs at presentation (P = 0.01). Abnormal SNAP cPL test results were associated with increasing age (P = 0.01). CLINICAL RELEVANCE: SNAP cPL test results are mostly reliable but can still be abnormal in a small percentage of dogs with GIFBO. Abnormal results in dogs without pancreatitis occurred more frequently in older dogs of the present study. Abdominal imaging is advised for dogs with abnormal SNAP cPL test results.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35482568/