Peer-reviewed veterinary case report
Dog with multiple skin nodules diagnosed with dermal dysplasia
By Uetsuka, K et al.·Published in Veterinary pathology·1999·View original on PubMed →
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Original publication title: Generalized dermal dysplasia and perifollicular mucinosis in a dog.
- Species:
- dog
Plain-English summary
A 1.5-year-old male mongrel dog had multiple skin nodules, ranging from 0.5 to 2 cm, on its back. The vet found that these nodules were related to a condition called generalized dermal dysplasia and perifollicular mucinosis, which involves abnormal skin cell growth. While the abstract does not specify treatment details, pets with similar skin issues often benefit from medications or topical treatments to manage symptoms and improve skin health. If your dog has unusual skin bumps, it's important to consult your veterinarian for an accurate diagnosis and appropriate care.
People also search for: dog skin nodules treatment · mongrel dog skin problems · generalized dermal dysplasia in dogs
Abstract
Multiple nodules 0.5-2 cm in diameter were observed in the dorsal skin of a 1.5-year-old male castrated mongrel dog. Histopathologically, perifollicular mucinosis and clusters of small cells with a dense, round nucleus and scant cytoplasm were seen. The small cell clusters were present in the dermis near the epidermal basal layer or surrounding hair follicles. These cells demonstrated different staining patterns for vimentin and keratin depending on their location; ultrastructurally, they were poor in organelles and connected to each other with cytoplasmic projections. These findings suggested that they were immature epithelial cells. The case was diagnosed as generalized dermal dysplasia and perifollicular mucinosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9921762/