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Peer-reviewed veterinary case report

Genetic characterization of a betanodavirus isolated from a clinical disease outbreak in farm-raised tilapia Oreochromis niloticus (L.) in Thailand.

Journal:
Journal of fish diseases
Year:
2015
Authors:
Keawcharoen, J et al.
Affiliation:
Department of Veterinary Microbiology

Abstract

Betanodavirus infection was diagnosed in larvae of farm-raised tilapia Oreochromis niloticus (L.), in central Thailand. Extensive vacuolar degeneration and neuronal necrosis were observed in histological sections with positive immunohistochemical staining for betanodavirus. Molecular phylogenetic analysis was performed based on the nucleotide sequences (1333 bases) of the capsid protein gene. The virus strain was highly homologous (93.07-93.88%) and closely related to red-spotted grouper nervous necrosis virus (RGNNV).

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24164433/