Peer-reviewed veterinary case report
Genetic characterization of equine adenovirus type 1.
- Journal:
- Veterinary microbiology
- Year:
- 2012
- Authors:
- Cavanagh, Heather M A et al.
- Affiliation:
- School of Biomedical Sciences · Australia
- Species:
- horse
Abstract
Two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV-1) and equine adenovirus type 2 (EAdV-2) have been isolated from horses. EAdV-1 is predominantly associated with upper respiratory tract infections while EAdV-2 appears to be associated with gastrointestinal infections in horses. In this report the EAdV-1 genome has been sequenced for the first time. The EAdV-1 genome encoded genes are characteristic of the Mastadenovirus genus such as protein V and IX. Unexpectedly, phylogenetic reconstructions also revealed a close relationship between EAdV-1 and two recently characterized bat adenoviruses. The results of this study suggest that EAdV-1 may share a common ancestor with canine and bat adenoviruses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21924564/